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Cancer was the greatest cause of health burden in Australia in 2011, accounting for around one-fifth of the total disease burden. Most (94%) of this burden was due to dying prematurely, with only a small proportion of the burden due to living with a cancer diagnosis. This report explores in further detail the burden of cancer in Australia, including cancer burden in Aboriginal and Torres Strait islander people, and by remoteness and socioeconomic group. It also looks at how the cancer burden has changed since 2003, and the potential burden of cancer expected in 2020.