The purpose of this paper is to explore how such questions and concepts of resilience may apply in the complex setting of a metropolitan region, that is, to understand what we'll call "regional resilience." How might regions, like individuals, adapt to adversity and stress? What factors account for a region's resilience and how can we measure them? As with individuals, given clear differences in challenges, assets and cultures, is it possible to compare places on the basis of their regional resilience? Can regions intervene to increase their resilience and, if so, why might a region fail to intervene well or at all?