Abstract: Interurban connectivity is a key theme within urban research. Cities mediate myriad flows through the actors and institutions within them, with ‘relational’ perspectives framing cities as sites of network convergence. Of particular interest has been the international dimension of interurban connectivity, and many researchers have sought to understand the interface between globalisation and urbanisation in the wake of neo-liberal and post-industrial restructuring that has fundamentally altered the global urban landscape. Taking inspiration from Brisbane’s recent marketing campaign which has positioned it as ‘Australia’s New World City’, this paper investigates multiple dimensions of Brisbane’s global networks. Innovating upon established theory in the ‘global cities’ tradition, Brisbane’s global position is analysed by quantifying various flows, including physical flows through Brisbane’s port, knowledge flows through exogenous research linkages, and human capital flows through Brisbane’s universities. Together, these networks provide a broad perspective on Brisbane’s global position and serve to advance understandings of how ‘global’ or ‘worlded’ claims might be substantiated through an empirical understanding of multiple flows. Although ‘global city’ status is elusive for Brisbane and other medium-sized cities, this paper makes the case that such cities are in fact global in many ways and that the specific connectivities of each should be better understood with regard to internationally oriented development policy.