This article describes the attributes that have underscored the success of the 45 and Up Study and demonstrate its value by reflecting on two case studies - research on socioeconomic inequalities in cardiovascular disease and the harms of smoking.

This report aims to provide a systematic overview of the contemporary evidence on the health effects of nicotine and non-nicotine e-cigarette use excluding, where possible, use of tetrahydrocannabinol (THC) and other illicit substances. The report was informed by the National Health and Medical Research Council of Australia E-cigarettes Working Committee stakeholder consultations, and underwent expert...