Arthritis
Strategy
Time to move: arthritis
The strategy outlined in this document provides a road map for improving care across Australia for people with arthritis and aims to reduce the costs to society of arthritis related diseases. The strategy is supported by three additional documents which respectively address the care of people with osteoarthritis, rheumatoid arthritis and juvenile idiopathic arthritis: Time...
Thesis
Investigation of the Genetic Link Between the Metabolic Diseases Gout and Type 2 Diabetes
Gout is associated with various co-morbidities including insulin resistance and type 2 diabetes. Gout and type 2 diabetes are strongly linked to the individual components of metabolic syndrome. There may be shared pathogenic pathways between gout and type 2 diabetes in which insulin resistance, obesity, hypertension and hyperuricaemia play a central role.Genetic and environmental factors...
Thesis
Lipoproteins and Hyperlipoproteinemia: Links to Gout
Gout and cardiovascular disease are both complex and multi-factorial with genetic predisposition and environmental triggers. Not only do both have high co-morbidity with other metabolic conditions, gout patients have high risk for cardiovascular events. Māori and Pacific populations have high risk for both gout and cardiovascular disease. The general aim of this study was to...
Thesis
The role of SLC2A9 Variants in Hyperuricemia and Gout
Gout is a debilitating arthritis caused by elevated levels of serum urate in the blood (hyperuricemia). The prevalence of gout is on the rise worldwide with particularly high rates of the disease present in Māori and Pacific populations in New Zealand (9.3-13.9% of Māori men and 14.9% of Pacific Island men affected). Genetic and environmental...
Thesis
Negotiating Barriers: An Investigation of Early Access to Rheumatology Services for Patients with Inflammatory Arthritis in the Wellington Region
Inflammatory arthritis (IA) is term that encompasses a range of auto-immune joint diseases that can cause severe pain, joint erosion and disability. Although there is no cure for these IAs, early treatment beginning within three months of symptom onset with disease-modifying anti-rheumatic drugs can significantly improve patient outcomes (Combe et al., 2007; Dixon Woods, et...