Over the 15 years since the 45 and Up Study was established, researchers have harnessed its capacity for enabling rigorous, comprehensive investigation of cancer causes, care, and outcomes. This paper uses lung cancer as a case study to demonstrate the Study’s potential to improve cancer control.

This narrative review explores the value and contribution of the 45 and Up Study - Australia’s largest longitudinal study of healthy ageing - to our understanding of factors that enable people to age well, widening inequities as people age, and prospects for healthy ageing for current and subsequent generations.

Frailty is an age-related clinical state associated with deterioration across multiple physiological systems and a leading cause of morbidity and mortality later in life. This review summarises evidence from longitudinal studies on frailty trajectories, transitions and trends.

The results of this study indicate that machine learning methods are well suited for predicting pre-frailty, and indicate a range of factors that may be useful to include in targeted health assessments to identify pre-frailty in middle aged and older adults.

This report measures the social impact of 'Meals on Wheels' and the importance of meaningful customer and volunteer connection, further supporting the essential role the service plays within almost every Australian community.