Abstract: Melbourne is ranked as the most liveable global city in the world. It is also one of the prominent destinations of knowledge workers. However, the global city literature has paid little attention to the important issue of migrant knowledge workers. Underpinned by Richard Florida’s ‘creative class’ theory, this paper investigates migrant knowledge workers by using global Melbourne as a case study. The research analyses the spatial distribution of their place of work and place of residence to identify the different patterns between international and internal migrant knowledge workers. The results illustrate that the knowledge workers, migrant knowledge workers in particular, tend to live and work in the inner city areas, where there are usually more diversity, tolerance and infrastructure. These findings have resemblances with Richard Florida’s 3T proposition, but extend the application to broader knowledge workers a global city context.