This Great Southern Regional Investment Blueprint will guide the region’s progress towards its vision for the period to 2040. To do this, it establishes a strategic framework for development across the region in all facets of life. It seeks to transform the way the different levels of government coordinate infrastructure development and service delivery, while attracting an increasing level of investment from the private and not-for-profit sectors to drive job creation, economic growth and community sustainability. Achieving the vision will mean building on existing areas of comparative advantage, leveraging beneficial outcomes from emerging global trends, maximising connections to national and international markets, and improving social and environmental outcomes in a time of dynamic change. Developing the Regional Blueprint involved more than two years of research and analysis that included assessing regional issues, cross-regional connections and global trends, and conducting a strategic review of the region’s comparative advantages and challenges. Concurrent with this research and analysis, key stakeholders were consulted from private enterprise, community service providers and government. This process built a vision for the future, established a range of aspirational targets and identified transformational opportunities to meet these targets. Local government was a key contributor and will have a vital role in realising these opportunities.