The design of environmentally-friendly buildings relies on the work of interdisciplinary teams who have to look at problems in a holistic way. Teams need to communicate, collaborate, and make decisions not solely based on first cost considerations. For this purpose, Target Value Design (TVD) related practices are being used to deliver green buildings in Southern California while meeting strict code requirements and addressing the needs of multiple stakeholders in a collaborative fashion. This study did not quantify costs associated with design and construction of sustainable buildings. It used an analytical process that compared and contrasted available literature on TVD and interviews with industry practitioners to investigate the use of TVD-inspired practices in the construction industry in Southern California and identify the current use of TVD-inspired practices in the design of green buildings. The study revealed that, even though practitioners might not be aware of how TVD can be fully implemented in these projects, a number of TVD-inspired practices are currently being used. Examples are provided to illustrate their practical use in the design of sustainable buildings and how practice compares to theory regarding TVD implementation.